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by Tudor Toma

RESEARCH ROUND-UP

Uncoupling protection
Mitochondrial uncoupling proteins are activated by superoxide and may protect against reactive oxygen species.

Email: Tudor Toma - t.toma@ic.ac.uk
News from The Scientist 2002, 3(1):20020107-02

Published 7 January 2002

Uncoupling proteins (UCPs) are molecules that usually generate heat in the mitochondria of brown adipose tissue, but their function in other tissues remains unclear. In 3 January Nature, Karim Echtay and colleagues from the Medical Research Council's Dunn Human Nutrition Unit, Cambridge, UK, show that UCPs may have a role in decreasing reactive oxygen species concentrations inside mitochondria.


 

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