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by Tudor Toma

RESEARCH ROUND-UP

p53 controls ageing
Mice overexpressing p53 are resistant to tumor development but exhibit early onset of ageing.

Email: Tudor Toma - t.toma@ic.ac.uk
News from The Scientist 2002, 3(1):20020107-03

Published 7 January 2002

The p53 protein works to suppress cancer cells by the induction of senescence, apoptosis and cell cycle arrest, but its role in the longevity of organisms remains unknown. In 3 January Nature, Stuart Tyner and colleagues from Baylor College of Medicine, Houston, USA, show that p53 has a role in controlling ageing in mice.


 

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