The riddle of the pharynx - The Scientist - Magazine of the Life Sciences

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by Jonathan B Weitzman

RESEARCH ROUND-UP

The riddle of the pharynx

Microarray analysis of worms identifies a genetic programme involved in organogenesis of the pharynx.

Email: Jonathan B Weitzman - jonathanweitzman@hotmail.com
News from The Scientist 2002, 3(1):20020205-01

Published

5 February 2002

The pharynx of Caenorhabditis elegans is a neuromuscular organ responsible for pumping food in from the environment and for initiating digestion. Organogenesis of the pharynx involves complex patterning and morphogenesis events, and the differentiation of distinct precursor cells. In the February 1 Science, Gaudet and Mango from the University of Utah report a genomic analysis of the role of the PHA-4 protein, a homologue of the forkhead box A (FoxA/HNF3) transcription factor involved in pharyngeal development (Science 2002, 295:821-825).


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