The Scientist : New model of autoimmune arthritis [18/3/2002]

Email: Tudor Toma - t.toma@ic.ac.uk
News from The Scientist 2002, 3(1):20020318-02

18 March 2002

Autoimmune arthritis is triggered by a systemic self-reactivity but why joints are the main targets for the specific inflammatory lesions remains unclear. Two papers in March 18 online Nature Immunology describe how antibodies to a ubiquitous cytoplasmic enzyme can provoke joint-specific autoimmune disease.

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