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Plasmid may have led to bubonic plague
Email: Tudor Toma - t.toma@ic.ac.uk News from The Scientist 2002, 3(1):20020429-02
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Yersinia pestis, the flea-borne agent of bubonic plague, is associated with two plasmids, the roles of which were not known. In 26 April Science, B. Joseph Hinnebusch and colleagues from National Institute of Allergy and Infectious Diseases, show that a plasmid-encoded phospholipase D is required for survival of Y. pestis in the midgut of its principal vector, the rat flea Xenopsylla cheopis (Science 2002, 296:733-735).
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