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Housekeeping clusters
There is controversy over the function of large clusters of co-expressed genes in the human genome.
Email: Jonathan B Weitzman - jonathanweitzman@hotmail.com News from The Scientist 2002, 3(1):20020510-01
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Operons, clustered groups of co-expressed genes, are well known in prokaryotes, but few examples exist in eukaryotic organisms. The availability of extensive transcriptome and genomic data for many eukaryotes is encouraging researchers to look more closely for clusters of co-regulated genes in higher organisms. In an Advanced Online Publication in Nature Genetics Martin Lercher and colleagues at the University of Bath, UK, report the existence of clusters of housekeeping genes in the human genome (Nat Genet 2002, DOI:10.1038/ng887).
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