The Scientist : Choosing the X [13/5/2002]

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by Jonathan B Weitzman

RESEARCH ROUND-UP

Choosing the X

Genetic crosses in mice have identified autosomal loci that affect the choice of X chromosome to be inactivated.

Email: Jonathan B Weitzman - jonathanweitzman@hotmail.com
News from The Scientist 2002, 3(1):20020513-01

Published

13 May 2002

Inactivation of one of the two X chromosomes in females is regulated by sequences on the X-chromosome within the X inactivation center (Xic). In the May 10 Science, Percec et al. report the identification of trans-acting autosomal elements involved in choosing the particular X chromosome for inactivation (Science 2002, 296:1136-1139).

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