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Stem cells live long and prosper
Email: Tudor Toma - t.toma@ic.ac.uk News from The Scientist 2002, 3(1):20020624-02
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Bone marrow stromal stem cells (BMSSCs) have a limited in vitro differentiation potential and are observed to senescence and die after no more than 30-40 population doublings (PD). But, two papers in June Nature Biotechnology, show that overexpression of telomerase in human bone marrow stromal cells extends their life span and maintains their osteogenic potential.
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