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Targeting human transgenes
Email: Jonathan B Weitzman - jonathanweitzman@hotmail.com News from The Scientist 2002, 3(1):20020702-01
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Adeno-associated viruses (AAVs) are single-stranded DNA vectors that have shown promise as gene-targeting vectors for experimental and therapeutic applications. In the July issue of Nature Biotechnology, Roli Hirata and colleagues at the University of Washington, Seattle, describe a way of using AAV to introduce a functional transgene cassette into defined genomic loci in human cells in culture (Nat Biotechnol 2002, 20:735-738).
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