The Scientist : Mutations in mental retardation [3/7/2002]

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by Jonathan B Weitzman

RESEARCH ROUND-UP

Mutations in mental retardation

Email: Jonathan B Weitzman - jonathanweitzman@hotmail.com
News from The Scientist 2002, 3(1):20020703-01

Published

3 July 2002

The genetic and molecular basis of mental retardation, which may affect up to 3% of the human population, is unclear. In the 28 June Science, Virginie Vervoort and colleagues report that mutations in the AGTR2 gene, encoding the angiotensin II receptor may affect cognitive function in people with X-linked mental retardation (XLMR). Linkage analysis of XLMR families suggested that the Xq23-25 region might contain more than one gene related to the disease (Science 2002, 296:2401-2403).

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