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Runt repression
Email: Jonathan Weitzman - jonathanweitzman@hotmail.com News from The Scientist 2002, 3(1):20020801-01
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The transcription factor Runt can repress expression of the Drosophila segment-polarity gene engrailed (en) in the odd-numbered stripes of expression seen in the developing Drosophila embryo. In an Advanced Online Publication in Nature Genetics John Wheeler and colleagues describe a genetic screen for factors that potentiate Runt activity (Nat Genet 2002, DOI:10.1038/ng942).
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