The Scientist : More on tumor suppression [7/8/2002]

Email: Tudor Toma - t.toma@ic.ac.uk
News from The Scientist 2002, 3(1):20020807-03

7 August 2002

The cyclin-dependent kinase inhibitor p27^Kip1 blocks cell division in response to antimitogenic signals, but the precise mechanisms behind this tumor suppression activity has been unclear. In July 31 early online edition of the Proceedings of the National Academy of Sciences Harry Hwang and colleagues at the Fred Hutchinson Cancer Research Center, Seattle, US, show that p27^Kip1 collaborates with a number of newly identified oncogenes to induce tumor suppression.

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