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by Tudor P Toma

RESEARCH ROUND-UP
Hck unleashes lung inflammation

Email: Tudor P Toma - news@biomedcentral.com
News from The Scientist 2002, 3(1):20020906-04

Published 6 September 2002
Hck is a Src family cytoplasmic protein tyrosine kinases with roles in cellular proliferation and migration, but its involvement in lung diseases such as asthma and chronic bronchitis (COPD) was not know. In September 3 Journal of Experimental Medicine Matthias Ernst and colleagues from Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Australia, show that constitutive activation of the Hck gene results in spontaneous pulmonary inflammation and an enhanced innate immune response in mice.


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