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Regulating large chromatin domains
Email: Jonathan Weitzman - jonathanweitzman@hotmail.com News from The Scientist 2002, 3(1):20021010-01
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The thymocyte-specific special AT-rich sequence binding 1 (SATB1) protein binds to base unpairing regions (BUR) within matrix attachment regions and assembles a SATB1 network structure that can regulate gene expression over relatively large distances. In the October 10 Nature, Dag Yasui and colleagues describe biochemical analysis of SATB1 within BUR-binding complexes (Nature, 419:641-645, October 10, 2002).
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