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Lupus susceptibility gene
News from The Scientist 2002, 3(1):20021028-01
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Systemic lupus erythematosus is an autoimmune disease for which a number of susceptibility loci exist, but the precise genes and mutations involved remain unclear. In October 28 advanced online Nature Genetics, Ludmila Prokunina and colleagues at the University of Uppsala, Sweden, show that a regulatory polymorphism in the programmed cell death 1 gene (PDCD1) is associated with susceptibility to systemic lupus erythematosus in humans (Nature Genetics, doi:10.1038/ng1020, October 28, 2002).
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