Imprinting and methylation :The Scientist [2/12/2002]

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by Jonathan Weitzman

RESEARCH ROUND-UP

Imprinting and methylation

Email: Jonathan Weitzman - jonathanweitzman@hotmail.com
News from The Scientist 2002, 3(1):20021202-01 doi:10.1186/20021202-01

2 December 2002

Parental-specific DNA methylation patterns are thought to regulate the establishment and maintenance of genomic imprinting. But the mechanisms controlling differential methylation and imprinting have been unclear. In an Advanced Online Publication in Nature Genetics, Christopher Schoenherr and colleagues describe a role for the zinc-finger protein CTCF in maintaining methylation at the Igf2/H19 imprinted locus (Nature Genetics, DOI:10.1038/ng1057, December 2, 2002).


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