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Il-4 calms psoriasis
News from The Scientist 2002, 3(1):20021202-02 doi:10.1186/20021202-02
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Psoriasis is an autoimmune disease of the skin and small joints characterized by Th1-mediated tissue destruction, and for which there is currently no efficient treatment. In December 2 Nature Medicine, Kamran Ghoreschi and colleagues at Ludwig-Maximilians University Munich, Germany, show that administering interleukin-4 to patients with psoriasis selectively deviate disease-inducing Th1 cells toward a Th2 phenotype and improves disease symptoms (Nature Medicine, doi:10.1038/nm804, December 2, 2002).
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