New cell proliferation blockers :The Scientist [6/12/2002]

Front Cover

Advertisement

NRW: North Rhine-Westphalia

Survey Series

The Scientist Daily

Science headlines delivered daily.
Register today.

Institutions

For Advertisers

by Tudor P Toma

RESEARCH ROUND-UP

New cell proliferation blockers

News from The Scientist 2002, 3(1):20021206-01 doi:10.1186/20021206-01

6 December 2002

Cellular senescence is a state of terminal arrest in which cells remain metabolically active for extended periods but can no longer respond to mitogenic stimulation. This can be exploited as a strategy to prevent tumorigenesis, but the molecular pathways involved in the induction of senescence remain unclear. In December 1 Journal of Clinical Investigation, Dimitri Lodygin and colleagues at the Max-Planck-Institute of Biochemistry, Munich, Germany, show that the drug LY83583 induces cellular senescence without inducing DNA damage (Journal of Clinical Investigation 110:1717-1727, December 1, 2002).


	The article you are attempting to read is Premium content which is only available to our online subscribers.

Subscribing to The Scientist is easy and inexpensive.

And you can choose from many options. Try us out with an online day pass starting at only $4.95. Or, get it all with unlimited online access to The Scientist Archive and door-to-door delivery of our monthly print magazine.


	The Scientist also offers site licenses to institutions and organizations. When your librarian adds The Scientist to the library's collection, you can get unlimited online access through your place of work or study. Recommend The Scientist today