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INK and ARF in chicks
Email: Jonathan Weitzman - jonathanweitzman@hotmail.com News from The Scientist 2002, 3(1):20021230-03 doi:10.1186/20021230-03
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The mammalian CDKN2A locus contains a gene encoding two unrelated proteins; the cyclin-dependent kinase inhibitor p16INK4a and ARF — a regulator of p53 stability. In the Early Edition of the Proceedings of the National Academy of Sciences, Soo-Hyun Kim and colleagues report that the chicken genome lacks an INK4a orthologue and has a truncated ARF gene (PNAS, 10.1073/pnas.0135557100, December 27, 2002).
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