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Discovering metabolic loci
Email: Jonathan Weitzman - jonathanweitzman@hotmail.com News from The Scientist 2003, 4(1):20030120-01 doi:10.1186/20030120-01
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Bacterial genomes often contain clusters of genes involved in secondary metabolite biosynthesis, that are not expressed until induction by specific chemical or physical stimuli. In an Advanced Online Publication in Nature Biotechnology, Emmanuel Zazopoulus and colleagues describe a high-throughput genome scanning method to detect such clusters in bacterial genomes (Nature Biotechnology, DOI:10.1038/nbt784, 20 January 2003).
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