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Longevity receptors
News from The Scientist 2003, 4(1):20030124-02 doi:10.1186/20030124-02
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Food restriction is a potent environmental variable and has been shown to increase longevity in diverse organisms, but how food availability affects life span has been unclear. In the January 24 Science, Matthias Blüher and colleagues at Georgetown University, Washington DC, USA, show that a reduction of fat mass without caloric restriction can be associated with increased longevity in mice, possibly through effects on insulin signaling (Science, 299:572-574, January 24, 2003).
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