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Imprinted by Eed
Email: Jonathan Weitzman - jonathanweitzman@hotmail.com News from The Scientist 2003, 4(1):20030310-02 doi:10.1186/20030310-02
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Imprinted genes are subject to epigenetic regulation and undergo parent-of-origin-specific allelic silencing. Many imprinted genes have been shown to contain a differentially methylated region (DMR). In an Advanced Online Publication in Nature Genetics, Jesse Mager and colleagues at the University of North Carolina at Chapel Hill, US, report a role for the Polycomb group protein Eed (embryonic ectoderm development) — a histone methyltransferase — in epigenetic regulation at imprinted loci (Nature Genetics, DOI:10.1038/ng1125,10 March 2003).
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