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HIV's sugar shield
Email: Tudor P Toma - t.toma@imperial.ac.uk News from The Scientist 2003, 4(1):20030320-04 doi:10.1186/20030320-04
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Most individuals infected with HIV-1 develop neutralizing antibodies (Nab) capable of eliminating autologous viruses in vitro, but the role of these antibodies in vivo has been unclear. In the March 20 Nature, Xiping Wei and colleagues at the University of Alabama at Birmingham, US, show that HIV manages to escape the Nab response through mutations in the env gene and selected changes in glycan packing (Nature, 422:307-312, March 20, 2003).
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