Dioxins' estrogen connection :The Scientist [29/5/2003]

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by Andrea Rinaldi

RESEARCH ROUND-UP

Dioxins' estrogen connection

Email: Andrea Rinaldi - rinaldi@unica.it
News from The Scientist 2003, 4(1):20030529-01

Published

29 May 2003

Dioxins are widespread by-products of many industrial processes. Exposure to these environmental contaminants can cause cancer and infertility. In particular, dioxins are known to either promote or antagonize the effects of estrogens—steroid hormones that regulate the function of reproductive tissues and other organs—although the molecular details of these estrogen-related actions remain unclear. In the May 29 Nature, Fumiaki Ohtake and colleagues at the University of Tokyo describe how dioxins alter cellular responses to estrogens in cultured cells and mice (Nature, 423:545-550, May 29, 2003).


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