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Neurons kiss and run
Email: Tudor P Toma - t.toma@imperial.ac.uk News from The Scientist 2003, 4(1):20030605-01
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The speed at which the limited pool of synaptic vesicles can be replenished controls the rate of synaptic transmission. Collapse and slow retrieval of synaptic vesicles is involved in the mechanisms that operate at synapses in some neurons, but the details of these processes in the central nervous system have been unclear. Two papers in the June 5 Nature show that large fractions of neurotransmitter release events in hippocampal synaptic terminals involve mainly "kiss-and-run," not vesicle, collapse.
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