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Recipe for hearing cells
Email: Tudor Toma - t.toma@imperial.ac.uk News from The Scientist 2003, 4(1):20031028-01
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Irreversible hearing loss can be age-related, congenital, or acquired during childhood and is due to the inability of the cochlear sensory epithelium to replace hair cells. Transplantation of progenitor cells capable of differentiating into hair cells could be potentially therapeutic, but a reliable source for these progenitors in not known. In the October 27 PNAS, Huawei Li and colleagues from Harvard Medical School show that cochlear hair cells can be generated by stepwise differentiation of embryonic stem (ES) cells (PNAS, DOI:10.1073/pnas.2334503100, October 27, 2003).
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