The Scientist : How meiotic arrest happens [13/12/2004]

Email: Cathy Holding - cathy.holding@absw.org.uk
News from The Scientist 2004, 5(1):20041210-01

13 December 2004

The mystery of how meiotic arrest is maintained in mouse oocytes is revealed this week in Science by Lisa M. Mehlmann and colleagues at the University of Connecticut Health Center. The team reports that meiotic arrest requires the presence of a G-protein–coupled receptor in the oocyte that elevates cAMP, which has been previously shown to be critical for preventing completion of meiosis.

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