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Novel angiogenesis mechanism
Email: Clementine Wallace - clementine.wallace@gmail.com News from The Scientist 2005, 6(1):20050718-01
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Tumor cells can trigger angiogenesis by a process involving physical contact with neighboring endothelial cells, scientists report in this month's issue of Cancer Cell. This is the first time, according to the paper, that such a mechanism has been described involving the Notch pathway, which is known to play key roles in embryonic vascular development and angiogenesis, but whose participation in tumor angiogenesis has been unclear.
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