Leukemia and Cancer Stem Cells :The Scientist [2006-04-01]


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	BY IRVING WEISSMAN AND MICHAEL CLARKE

Leukemia and Cancer Stem Cells Cancers and normal tissue stem cells have much in common: Both have self-renewal capacity, and both develop into differentiated progeny. But do true cancer stem cells exist? We believe that they do and that this realization will have a major impact on the understanding and treatment of cancers. Putative cancer stem cells can be recognized by three attributes: They constitute a homogenous cell