Kenneth Chien, director of the Massachusetts General Hospital Cardiovascular Research Center and a professor in the Department of Cell Biology at Harvard Medical School, says that the regenerative qualities of stem cells hold great long-term promise in treating heart disease. But the scientific vision of cardiac muscle regeneration has yet to be proven in clinical trials, and a growing body of evidence suggests that any benefits may actually be due to a secondary effect rather than to the regenerated cardiac muscle cells themselves. On page 34, he writes about the lessons learned from these early trials, which he calls a "parable for regenerative medicine."
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