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Supplement: Smoking and Rheumatoid ArthritisRecently, Lars Klareskog at the Karolinska Institute and his colleagues described a strong gene-environment interaction in a subset of people with rheumatoid arthritis (RA) (L. Klareskog et al., "Genes, environment, and immunity in the development of rheumatoid arthritis," Curr Opin Immunol, 18:650-5, 2006.) "It was well established that smoking is a risk factor in RA, but no one knew why," says |
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