Supplement: Manipulating the Mechanisms :The Scientist [2007-05-01]


	The article you are attempting to read is Premium content which is only available to our online subscribers.

Subscribing to The Scientist is easy and inexpensive.

And you can choose from many options. Try us out with an online day pass starting at only $4.95. Or, get it all with unlimited online access to The Scientist Archive and door-to-door delivery of our monthly print magazine.


	The Scientist also offers site licenses to institutions and organizations. When your librarian adds The Scientist to the library's collection, you can get unlimited online access through your place of work or study. Recommend The Scientist today



Supplement: Manipulating the Mechanisms There is a plethora of different kinds of mechanisms that are being pursued that are, to me, very exciting. If I focus primarily on one disease, say, rheumatoid arthritis, we now have a number of anti-TNF [tumor necrosis factor] agents: Enbrel, Humira, Remicade, and now Cimzia, all of which basically target the TNF overproduction. After the anti-TNFs, there are a number of therapies for arthritis