For those frustrated by the brute force of knockout mice when studying gene function, in vivo RNA interference (RNAi) would seem to have come to the rescue. In theory, in vivo RNAi promises a more nuanced approach that gives researchers temporal and spatial control in knocking down genes.
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A Nuanced Knockout
If using in vivo RNAi has you down for the count, here's what you need to know.
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