The Small Side of Cancer

Can microRNAs help diagnose, classify, and stage human cancers?

In 2002, George Calin, Carlo Croce, and colleagues at Thomas Jefferson University provided the first evidence that microRNAs — small noncoding RNAs that can repress gene expression — were linked to cancer.1 Since then, the field has mounted a massive effort to find out whether those links will be clinically useful.

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