Like many researchers who had to run hundreds of Southern blots, I felt immediate relief the first time I used PCR for genotyping. It was no longer going to take seven days to see results, and I would never again have to use micrograms of DNA or handle radioactivity. In the years that the technology has grown, PCR has revolutionized both genomics and transcriptomics. It may even play into proteomics studies as immuno-PCR gains popularity.







