News:
The state of science in South Africa
Posted by Stephen Pincock
[Entry posted at 4th April 2006 05:38 PM GMT]
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Sixty-one years ago, South Africa's Council for Scientific and Industrial Research was established by a parliamentary decree that specifically required it to undertake research that improves the wellbeing of the country's people.

Given this, I wasn't really surprised, on visiting CSIR's sprawling campus on the outskirts of the city of Pretoria, to find biosciences researchers focusing on issues to do with HIV, malaria, tuberculosis and improving nutrition. I dropped by the campus during my 10 day trip to Africa on behalf of The Scientist to survey the region?s science.

In the plant biotechnology group, for example, group leader Rachel Chikwamba showed me around one lab where investigators are using microarrays and proteomics to examine lead compounds from indigenous plants as potential antimalarials.

Down the hall, she introduced me to investigators who have had some success in producing plants that express a rabies monoclonal antibody. In the greenhouses outside, her group is growing transgenic sorghum -- an African crop plant. In one project their aim is to develop sorghum lines with nutritional enhancements such as added vitamins, amino acids, iron or zinc.

And elsewhere in the building, Makohetsa Khati told me that he is building on work he conducted at Oxford University to utilize aptamer technology for developing novel antiretrovirals and diagnostic tools for diseases like tuberculosis.

As the CSIR's group manager for research and development, David Walwyn, told me this morning, South Africa's research strengths have long included the medical and biological sciences. Given some of the enormous health challenges facing the country today, this is at least something to be thankful for.


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