On The Life Sciences Scene

Science Marches On

Sleep Is A Biological Enigma?
and
Sleep Protects Against Traffic Accidents

A. From "A good night's sleep protects against parasites"

http://www.eurekalert.org/pub_releases/2009-01/bc-agn010709.php

- "Sleep is a biological enigma. Despite occupying much of an animal's life, and having been scrutinized by numerous experimental studies, there is still no consensus on its function".

- "When asleep, animals largely avoid....activities, and can thus allocate resources to the body's natural defenses."

B. Sleep made simple: it is an inherent Earthlife trait

- Every organiasm sleeps because its genes-genomes sleep. And sleep is innate for genes because genes, being the first organisms evolved on Earth, came into being, born, by the sun's radiation energy absorbed by RNA-conformations oligomers, and the newborn genes were active ONLY when exposed to sunlight, which was then their only usable energy. Thus sleep is an inherent Earthlife trait.

- When asleep in bed, drivers largely avoid activities, and can thus allocate resources to the body's natural defenses against traffic and other accidents.

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Life's Manifest
http://www.the-scientist.com/community/posts/list/112.page#578

Further Elaboration Of Horizontal Gene Transfer

"Structure mediating spread of antibiotic resistance identified"
http://www.eurekalert.org/pub_releases/2009-01/wt-sms010709.php

Horizontal (lateral) gene transfer is incorporation, in an organism, of genetic material from another organism without being the offspring of that organism (versus vertical transfer, when an organism receives genetic material from its ancestor). The transfer is by a 'secretion process', of elaborating and releasing materials from within a cell. This work elaborates the role of Type IV sub-system, a component of the secretion system.

'Mediate' is a transitive verb that means to effect by action as an intermediary, to transmit as intermediate mechanism or agency. Spread of antibiotic resistance proceeds by horizontal gene transfer, that produces extremely dynamic genomes in which substantial amounts of DNA are introduced into (and deleted from) the chromosome, by transformation or conjugation or transduction.

Nice work and elaboration. But I cringe involuntarily at references as 'DNA materials' to genes and/or genomes, and at implying that 'the cell' does anything. For me it has been obvious for many years that genes and genomes are organisms and that all structures within the outer cell membrane (OCM), including the OCM, are functional organs of the genes-genomes, that we are discussing the members (genes) of the spaceship (cell) team (genome)...

Dov Henis
(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Life's Manifest
http://www.the-scientist.com/community/posts/list/112.page#578

Aging Not Approachable With Oversimplification
The Aging Chain
Aging genes age genomes age cells age cellular organisms And Vice Versa

A. "Sirtuin shown to control gene activity"
http://www.sciencenews.org/view/generic/id/39788/title/Sirtuin_shown_to_control_gene_activity_
A previously overlooked protein called SIRT6 provides some molecular clues to aging.

Chua’s and Chang’s groups together show that SIRT6 works with a master regulatory complex called NFkappa-B to govern activity of genes associated with aging, inflammation, immunity and metabolism. When SIRT6 is missing, NFkappa-B becomes hyperactive and turns up activity of aging-linked genes.

Mostoslavsky believes many important body systems are affected by SIRT6, but cautions that the enzyme is not necessarily an anti-aging protein. The mutant mice lacking the protein have severe metabolic disturbances that could account for premature aging. Researchers have not yet detected any change in SIRT6 levels or activity with age.

“Whether this has a role in the normal aging process, we still don’t have enough information to answer that,” he says.

B. Aging, lifetime and age

Aging = to become old, show the effects or the characteristics of increasing age, the increasing lifetime. The effects and characteristics of not only the totality of the system but also of each and every component and components of the components of the system. The system is the totality of the components.

lifetime = the duration of the existence of a living being, an organism, or an inanimate thing, a material, star or subatomic particle.

age = the length of an existence extending from the beginning to any given time.

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Life's Manifest
http://www.the-scientist.com/community/posts/list/112.page#578

Extra Extra, Read All About It,
Biological Evolution Discovered
By Mathematicians And Evolutionary Ecologist

A. From "Mathematicians show how beetles can share a niche"
http://www.sciencenews.org/view/generic/id/39715/title/Mathematicians_show_how_beetles_can_share_a_niche
New equations help solve decades-old puzzle of why one species does'nt always outcompete another.

Placing two species of flour beetle in the same jar of flour needn't always result in one species driving the other to extinction. A new mathematical model shows how sometimes these two competing species can coexist.

"It opens some questions about this dogmatic view in ecology...It reopens the issue of what you consider a niche to be."

In the novel illuminating case researchers noted a small evolutionary change in the traits of the beetles. They sometimes eat the eggs of their own species as well as those of closely related species. In this case they evolved to become more-voracious egg eaters.

Cushing and his colleagues designed a mathematical model that, unlike previous models, allowed the egg-eating trait to evolve — which affected the birth and death rates of each species. Neither species went extinct after more than 30 generations.

What makes this work very, very exciting, comments an evolutionary ecologist, is that it shows how just a tiny bit of evolution might actually explain the results... (end quotes)

B. What a thrilling scientific discovery!

How just a tiny bit of evolution might actually explain the results...the co-existence of competing species...

Wow! this may explain why in some niches some competing species struggle violently whereas in others they coexist thrivingly! And just think that this may apply to so many types and sizes of niches and to so many species! Wow! It may apply even to human societies!

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Life's Manifest
http://www.the-scientist.com/community/posts/list/112.page#578

Culture, A Ubiquitous Biological Entity
http://www.the-scientist.com/community/posts/list/98.page

On Humans (And Other Materials) Evolution
And On The Sad State Of Life Sciences In 2009

Re "Stanford researchers show adaptation plays a significant role in human evolution"
http://www.eurekalert.org/pub_releases/2009-01/su-srs011409.php

1) "For years researchers have puzzled over whether adaptation plays a major role in human evolution or whether most changes are due to neutral, random selection of genes and traits."

- I have been presenting evidence for years that adaptation, i.e. culture, is the driver of evolution of all life including human and, yes, of all other materials, and that genetic evolution is generally biased, not random.

2) "Geneticists at Stanford now...show adaptation, the process by which organisms change to better fit their environment, is indeed a large part of human genomic evolution."

- Shortly after retiring from industrial consulting (1956 - 1998) I started investigating the state of comprehension of the nature of life and of its evolution and I published evidence and conclusion that culture is the driver of all genomic evolution.

3) "Others have looked for the signal of widespread adaptation and couldn't find it...now...we were able to detect the adaptation signatures quite clearly"

- I found the evidence many years ago and presented it clearly in my postings.

4) "All genetic mutations start out random, but those that are beneficial to an organism's success in their environment are directly selected for and quickly perpetuate throughout the population, providing a uniform, traceable signature."

- NO NO NO. The drive of evolution is NOT RANDOM followed by survival selection. It is biased, as explained in my "Life's Manifest" and elaborated in my posts about the role of culture in evolution.

5) "Humans have a very complex history from traveling around the globe, and the human genome is also highly structured, making it complicated and difficult to work with, he said."

- The human genome, like all other genomes, is complicated, being a multi-genes organism, an organism that consists of a cooperative commune of the smaller Earth's primal organisms, namely of genes.

6)"Adaptation becomes widespread in the population very quickly," Petrov said. "Whereas neutral random mutation doesn't and would not have the selective sweep signature."

- Bravo. This happens to be a correct statement. Random mutations are mechanical accidents that the organism may or may not overcome to survive.

I stop here. No patience nor interest to continue picking at each of the following paras. Just sadly frustrated at The Sad State Of Life Sciences In 2009...

Respectfully yours,

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Life's Manifest
http://www.the-scientist.com/community/posts/list/112.page#578

Rethought Unified Field Theory And Evolution

A. SN Special : Darwin turns 200
http://www.sciencenews.org/view/feature/id/39754/title/SN_Special__Darwin_turns_200
This special web edition of Science News includes expanded versions of articles from the magazine's print edition plus two additional features, all commemorating the 200th anniversary of the birth of Charles Darwin.

B. 22nd Century Conception Of Unified Field Theory And Evolution

The following brief essays present the 22nd century comprehension of evolution. They preserve Darwin's name in reference to Life Evolution in respect and appreciation of Darwin's promotion of the concept of evolution in life.

Life's Manifest
http://www.the-scientist.com/community/posts/list/112.page#578

Culture, A Ubiquitous Biological Entity
http://www.the-scientist.com/community/posts/list/98.page

Life And Darwinian Evolution, 21st Century Comprehension
http://www.the-scientist.com/community/posts/list/112.page

Rethink Unified Field Theory And Evolution
http://www.the-scientist.com/community/posts/list/60/122.page#982

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

What Is Switched When Genes Are Switched

A. "Gene switch sites found mainly on 'shores,' not just 'islands' of the human genome"
http://www.eurekalert.org/pub_releases/2009-01/jhmi-gss011209.php

CpG islands are DNA regions containing a high frequency of CpG (cytosine-phosphodiester-guanine) dinucleotides, 300-3,000 base-pairs long in mammalians, often in-near 'promoters' of mammalian genes.

"Epigenetic finding adds insight on how cells become brain, liver or malignant"
http://www.eurekalert.org/pub_releases/2009-01/jhmi-lds011209.php

B. From "Epigenetic Heredity Comprehension Advanced"
http://www.the-scientist.com/community/posts/list/80/122.page#1118

These above works are outstanding, yet could be more elaborative and revealing if gene-genome are realized to be the organisms they are.

One day, maybe yet in the 21st century, science will look back with amused disbelief at old terms and concepts like "letters of the DNA sequence" and "epigenetic information", in regards to genes-genome organisms...

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Life's Manifest
http://www.the-scientist.com/community/posts/list/112.page#578

EVOLUTION Beyond Darwin 200

I.
At Darwin 200
Darwin Extended Beyond His Own Horizon
Rethought Unified Field Theory And Evolution

A. SN Special : Darwin turns 200
http://www.sciencenews.org/view/feature/id/39754/title/SN_Special__Darwin_turns_200
This special web edition of Science News includes expanded versions of articles from the magazine's print edition plus two additional features, all commemorating the 200th anniversary of the birth of Charles Darwin.

B. 22nd Century Conception Of Unified Field Theory And Evolution

The following brief essays present the 22nd century comprehension of evolution. They preserve Darwin's name in reference to Life Evolution in respect and appreciation of Darwin's promotion of the concept of evolution in life.

Life's Manifest
http://www.the-scientist.com/community/posts/list/112.page#578

Culture, A Ubiquitous Biological Entity
http://www.the-scientist.com/community/posts/list/98.page

Life And Darwinian Evolution, 21st Century Comprehension
http://www.the-scientist.com/community/posts/list/112.page

Rethink Unified Field Theory And Evolution
http://www.the-scientist.com/community/posts/list/60/122.page#982

II.
Evolution beyond Darwin 200

Per "Design And Randomness In Cosmic And Life Evolution"
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1&p=404

Singularity and D-Infinity (max expansion, energy dilution) are the cosmic end states. Their in-between is a metastable state. This corresponds to commonsense observation: the denser the compacting goal of material the more energy is required, and vice versa the more thorough the disintegration of material the higher the amount of energy released. It seems that the cosmic universal process is E=Total[m(1+D)] , where D is the Distance from Big Bang point and the sum is of all spatial values of D from D=0 to D=selected value.

Presently the cosmos expands on the right side of the equation. However, within its accelerating overall energy dilution there are local phenomena of formation of temporarily constrained energy pockets that evolve backwords towards impansion. The two most obvious examples of such backword energy constraints are black holes and life, two distant relatives within a probably big family of various forms of cosmic 'backlash energy constraints'.

Suggesting,

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

A Probable Natural Paradigm To Surgery Checklist

A. "Checklist reduces surgery complications"
http://www.sciencenews.org/view/generic/id/39871/title/Using_checklist_reduces_surgery_complications
Measure twice, cut once: Going over a checklist of procedures in the operating room before and after surgery lowers the complication rate and, in developing countries, saves lives, a study in eight hospitals shows.

B. A Probable Natural Paradigm...

From "How Decisions Are Made Within The OCM (outer cell membrane)"
http://www.physforum.com/index.php?showtopic=14988&st=180&#entry325606

... the genome behaves not as being presided by a decider President Gene, but by innate complete credence to each and every member of the cooperative genome commune of its genes membership, thus accepting a priori the decision of the individual member, but But BUt BUT coupling this with a very elaborate system of crisscross checklisting of this decision by other members of the genome.

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Life's Manifest
http://www.the-scientist.com/community/posts/list/112.page#578

Wake up.
Re-think-plan-do-assess Sleep Melatonin works.

Sleep, Melatonin, Cancers And Beyond Darwin 200

I.

Darkness, melatonin may stall breast and prostate cancers
http://www.sciencenews.org/view/generic/id/40170/title/Darkness%2C_melatonin_may_stall_breast_and_prostate_cancers_
New studies suggest strong links between melatonin and breast and prostate cancers.

Melatonin is a hormone produced in the pea-size pineal gland in the center of the brain, secreted at night or in the dark. It is used to regulate the sleeping cycle and also found to correlate with other functions and problems in the body.

II.

Sleep and chirality are biological evolution evidence that genes are organisms

From "Circadian Rhythm-Metabolism Link Is Self-Explanatory"
http://www.physorg.com/news136122147.html

"Circadian rhythm-metabolism link discovered" ?
http://esciencenews.com/articles/2008/07/24/circadian.rhythm.metabolism.link.discovered

The findings also suggest that proper sleep and diet could help maintain or rebuild the CLOCK-SIRT1 equilibrium and may help explain why lack of proper rest or disruption in our normal sleep patterns is known to increase hunger, which can lead to obesity and related illnesses and can accelerate the aging process.

II.

Circadian-rhythm is the genes' innate rest time,

which - together with life's chirality - are the earliest evidences of Darwinian life evolution, the evolution of the primal, 1st stratum, Earth organisms, the genes.

From "SC displaced more easily when off-duty":

"It is unclear why the stem cells leave their niche during a patient's time of rest"
[Dov Henis comment posted in TS, 2008-10-10]
http://www.the-scientist.com/blog/display/55081/

SC are more easily displaced during the organism's rest time simply because their genes and genome are off-duty then, part of the duty is to be responsively on-call at the specific site where they are:

"Life's Chirality And Circadian Rhythm, Evidence Of Updated Darwinian Evolution"

A. Updated life's concepts:

http://www.the-scientist.com/community/posts/list/20/122.page#423

- Earth life consists of three strata: genes are primal organisms, genomes are evolved 2nd stratum organisms, and cellular organisms are evolved 3rd stratum.

- Life's evolution started at genesis.

- Life's evolution is not random. It is biased, driven by culture.

B. Earliest evidences of updated Darwinian evolution:

- Life's chirality
http://www.the-scientist.com/community/posts/list/122.page#387
http://www.physforum.com/index.php?showtopic=14988&st=180&#entry327715

- Circadian rhythm
http://forum.physorg.com/index.php?showtopic=14988&st=135&#entry301299

III.

Circadian Rhythm-Metabolism Link Is Self-Explanatory, and new "findings" are not required for suggesting that proper sleep and diet could help maintain or rebuild organism's "equilibrium" and for explaining why lack of proper rest, or disruption in our normal sleep patterns, is known to cause several unhealthy things in us and accelerate our aging process.

Suggesting,

Dov Henis
(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Aging, Leakiness Of Nucleus Membrane
The Aging Whole Being A Construct Of Its Constituents

A. "As cells age, the nucleus lets the bad guys in"

http://www.sciencenews.org/view/generic/id/40136/title/As_cells_age%2C_the_nucleus_lets_the_bad_guys_in

A study tracks a growing 'leakiness' in the membrane of the cell nucleus that could contribute to aging and even to diseases such as Parkinson's and Alzheimer's.

B. The nucleus membrane is an organ, a functional organ of the genome organism

All biological materials, of all forms, 'age'-change with time and with environments-circumstances. The list of possible age-related pore-leakiness effectors comprises a variety of 'aging' facors that continuously modify the functionality of the pore and modify also the characteristics of the constituents of the inventory of materials within the outer cell membrane, the largest organ of the genome.

C. "Aging Not Approachable With Oversimplification". Aging Is A Closed Chain.

http://www.the-scientist.com/community/posts/list/100/122.page#1318

Aging genes age genomes age cells age cellular organisms and vice versa, the whole WHOLE being a construct of its constituents...

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Life's Manifest
http://www.the-scientist.com/community/posts/list/112.page#578

Beyond Darwin 200
Melatonin Switches On Mostly Intercell Maintenance
Wake up.
Re-think-plan-do-assess Epigenetics, Sleep And Melatonin works.

A. "Epigenetics reveals unexpected, and some identical, results"
http://www.sciencenews.org/view/generic/id/40060/title/Epigenetics_reveals_unexpected%2C_and_some_identical%2C_results
One study finds tissue-specific methylation signatures in the genome; another a similarity between identical twins in DNA’s chemical tagging.

I humbly suggest : Re-think-plan-do-assess Epigenetics Works, founded on scientific conception that genes and genomes are organisms.

B. "Sleep, Melatonin, Cancers And Beyond Darwin 200"
http://www.the-scientist.com/community/posts/list/100/122.page#1412

I humbly suggest: Re-think-plan-do-assess works, founded on scientific conception that genes and genomes are organisms.

C. Apparent functional aspects of melatonin
http://cogweb.ucla.edu/ep/Neurology.html#Melatonin

Melatonin is a hormone secreted by the human pineal gland during night-time darkness, and it is now being marketed in the US as a nutritional supplement. The hormone is an indoleamine compound derived from the amino acid *tryptophan, with *serotonin as an intermediate precursor.

1) The most important role of melatonin in all species is to provide a hormonal signal of night-time darkness. The secretion of the hormone is tightly controlled by the *circadian pacemaker. 2) Melatonin is a phylogenetically ancient hormone, found even in some single-cell organisms and in some plants. 3) At the cellular level, melatonin receptors are members of the superfamily of *G protein-coupled receptors...Activation of these receptors inhibits *cyclic AMP production by the enzyme adenylyl cyclase.

cAMP (cyclic AMP) acts as an intracellular hormone (i.e., a chemical messenger). Cyclic AMP is derived from ATP in a reaction catalyzed by the enzyme adenylyl cyclase (also called adenyl cyclase and adenylate cyclase).

I humbly suggest: Melatonin, the phylogenetically ancient hormone, was evolved by the genome during the early single-cells eons when they evolved community life cultures and graduated from sunlight-only to metabolism-too energy production. Melatonin's role was to signal that the genes are asleep, their functional activities are shut off, and it is time for the security and maintenance crews to do their tasks, especially to clean up the intercell environment, for keeping the community of cells in proper state.

D. It all adds up to:

Gene: a primal Earth's organism. (1st stratum organism)
Genome: a multigenes organism consisting of a cooperative commune of its member genes. (2nd stratum organism)

"Life's Manifest"
http://www.the-scientist.com/community/posts/list/112.page#578

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Prsdnt Obama Deludes Himself
Re The Required Economy Collapse Cure
It's Not Just The Economy, It's The Technology Culture That Collapsed

A. Brief notes re the apparent major aspects of the collapse

1) Jan 6 2009

What Is "Scientific Progress"
What Is Needed To Advance Science
http://www.physforum.com/index.php?showtopic=14988&st=390&#entry392722

2) Dec 24 2008

For 2008 Sciencenews Of The Year YOK The World-Wide Economy Collapse
Money Printing Will NOT Cure The Technology Culture Greed Cancer
http://www.physforum.com/index.php?showtopic=14988&st=390&#entry390280

3) Dec 22 2008

Separate Technology From Science To Renovate Our Culture Including Economy
http://www.physforum.com/index.php?showtopic=14988&st=375&#entry390004

4) Nov 21 2008

Real And Virtual Energy, And Keynesian Salvation Prospects
http://www.physforum.com/index.php?showtopic=14988&st=345&#entry384952

B. There are no short-cuts for effecting a cure of the malignant world economy greed cancer.

From the above (4) ref:

"The present tone of the world's culture, and even ethics, including the banners of a variety of types and shades of greed, has been set by the 20th century Technology Culture. Its essence is the legitimacy and admiration of gaining capital via virtual activities, activities without or beyond the production of real assets, real life resources.

So the odds of the economy's salvation via Keynesian prospects are, in the long run, proportional to the odds that the culture of Earth's humanity will evolve towards ever more rational self-organization...which is, how unsurprisingly rational, the odds of every organism to survive..."

There are no short-cuts for effecting a cure of the malignant world economy greed cancer. The cure and recovery from this cancer entails a steady resolute cultural modification of 20th century personal and societal capitalistic greed values-ethics-morals. It entails public education to value and promote legitimacy and respect only of shares-stocks of products and processes that contribute to health, security, basic comfort, education and science, and to reject and shun products and processes involved in any form of luxuriousness.

And it entails a steady resolute continuous promotion of respect to non-luxurious life style and to pursuit by science, of convincing, ever closer approaching, approximate models of the real world including life and ourselves. This would be a return to and furthering of Enlightenment's inherent philosophy and attitudes in regards to individualism, universal human progress and, most important to humanity, the applications of reason.

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Musicality Of Newborns

A. Newborns pick up the beat

http://www.sciencenews.org/view/generic/id/40245/title/Newborns_pick_up_the_beat
Electrical measurements of sleeping newborn babies’ brains indicate that the 2- to 3-day-olds automatically detect a regular beat in rhythmic sequences, possibly reflecting an early capacity for learning music.

B. Why Music Touches Us
Nov 11 2005, in biologicalEvolution forum

http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1&p=184

My conjecture about music 'touching-moving' us:

Music is a human cultural-artifactual elaboration of creatures' vocal communication which is an extension-elaboration of >24 wks-old in-womb fetus' and of newborns' intimate safe-coddle-sooth experiences. Both 'touch' and 'hear' senses are founded on mechanical sensing processes involving in-cell ions leakage forming electrical action potentials interpreted neurologically. I suggest-conjecture that the same neurological constellation may be handling both 'touch' and 'hear' senses, being of commom mechanisms and differing essentially only in switch-on modes, and that this evolves in all vocal creatures in conjunction with in-womb safe-feeling, and later with baby codling-handling and vocal soothing-communicating, and later also with intimate emotional implications. Hence music has 'engulfing-touching-emotional' connotation and individual's music orientation has childhood-ethnic rootings.

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Life's Manifest
http://www.the-scientist.com/community/posts/list/112.page#578

Pavlov's Smile
Ameisen Olivier, Imagination Medicine,
Placebo, God-Religion, Virtual Reality

(recapitulation of some earlier posts)

A. Anti-Depressants, like

- Ameisen Olivier's "end of my addiction"

- http://www.completehealthdallas.com/Anti-DepressantsNaturalAlternativeDallas.html

- http://www.answers.com/topic/serotonin

B. Imagination Medicine

http://www.sciencenews.org/view/feature/id/39046/title/Imagination_Medicine
Brain imaging reveals the substance of placebos. Expectation alone triggers the same neural circuits and chemicals as real drugs.

"It all boils down to expectation. If you expect pain to diminish, the brain releases natural painkillers. If you expect pain to get worse, the brain shuts off the processes that provide pain relief. Somehow, anticipation trips the same neural wires as actual treatment does.

Scientists are using imaging techniques to probe brains on placebos and watch the placebo effect in real time. Such studies show, for example, that the pleasure chemical dopamine and the brain’s natural painkillers, opioids, work oppositely depending on whether people expect pain to get better or worse. Other research shows that placebos can reduce anxiety."

C. Placebos: some background info

http://www.cerebromente.org.br/n09/mente/pavlov_i.htm
http://www.cerebromente.org.br/n09/mente/placebo1_i.htm
http://thjuland.tripod.com/placebos.html

The concept of a placebo comes from medieval times, when professional mourners were paid to stay by the bedside of. deceased person, reciting a psalm beginning "Placebo Domino..." or "I shall please the Lord." "Placebo" gradually became the word used for the paid mourner, whose grief was, in fact, false.

D. Life's Manifest

http://www.the-scientist.com/community/posts/list/112.page#578

Genes are the primal, 1st stratum, Earth's organism and genomes are 2nd stratum organisms,
multigenes consisting of cooperative communes of their member genes.

Life is a real virtual affair that pops in and out of existence in its matrix, which is the energy constrained in Earth's biosphere.

E. On Science and Religion

"Evolutionary Biology Of Culture And Religion"
http://www.the-scientist.com/community/posts/list/20/122.page#492

The concept “God” is a human virtual reality artifact, experienced only through sensory stimuli. Preoccupation with god-religious matters within a scientific frameworks contributes to corrosion and corruption of science and scientism by manifesting or implying acceptance of virtual reality as reality.

Everything is discussable scientifically. No limit. Including virtual matters and affairs. But for a scientific discussion the framework must be clearly defined. The totality of subjects that come under the classification "virtual" are not an exception. You can include in the discussion Pavlov and the modes and manners of exploiting virtuality in any area and towards any end.

F. So why Pavlov smiled in 2008?

Pavlov demonstrated effecting placebo phenomena in multicelled organisms by manipulation of their drives-reactions. Now placebo and imagination phenomena are demonstrated also in the smaller organisms, in the genes and genomes of multicelled organisms, in our primal first stratum and 2nd stratum base organisms. A very good reason to smile.

Now an interesting chain is exposed to our view, the Genes-Virtual Reality Chain, a most intriguing cultural evolution chain extending from the genesis of our genes to nowadays, throughout life, a virtual reality existence, and by virtual reality phenomena, exploitations and manipulations.

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Multicells-Life Date Pushed Back,
But With Confused Terminology

A. From "Animal ancestors may have survived ‘snowball Earth’"
http://www.sciencenews.org/view/generic/id/40580/title/Animal_ancestors_may_have_survived_%E2%80%98snowball_Earth%E2%80%99
Chemical fossils in Precambrian sedimentary rock push back the first date for animal life.

1) Finding a molecule that was made by an organism, means that the biosynthetic ability to make that molecule must have evolved earlier than the Cambrian period, which extended 544 to 500 million years ago with marine invertebrates. Biosynthetic ability had to be around by at least 635 million years ago and, the researchers say, maybe as early as 751 million years ago.

2) There’s evidence of eukaryotic life, organisms with DNA sequestered in a protective nucleus, from roughly 1.9 billion years ago, but proper multicellular animals don’t appear on the scene until much later.

B. Confused terminology

The report mostly and clearly attributes ONLY to multicells organisms the terms animal ancestors, animal life, organism, biosynthetic ability. Yet it terms also an 'organism' a maybe, probable, 1.9 billion yrs old 'eukaryotic life', even if implying that it might have not been 'proper multicellular animals'.

C. Suggested clarification of scenario and terminology

From "Life's Manifest"
http://www.the-scientist.com/community/posts/list/112.page#578

- First were independent individual genes, Earth's primal organisms.
- Genes aggregated cooperatively into genomes, multigenes organisms, with genomes' organs.
- Simultaneously or consequently genomes evolved protective and functional membranes, organs.
- Then followed cellular organisms, with a variety of outer-cell membrane shapes and
functionalities.
- Cellular organisms (3rd stratum organism): mono- or multi-celled earth organisms.

Since evolution is definitely driven by culture, the evolution of multicelled organisms was preceded by evolution of cooperative community life culture of the monocelled organisms. Most presently observed biological processes and internal organs in multicelled organisms have originated and evolved by and during the evolution of the cooperative community life culture of the monocelled organisms...

Suggesting,

Dov Henis
(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Peer Review In Science, Whereto?

A. "Google peer review"
http://www.the-scientist.com/community/posts/list/380.page#1497

Seeks comments on "crowd-sourcing the peer review process".

B. Enhancing Peer Review (NIH/OD)
Sent:Jan 03, 2009
To: henisdov
Subject:Peer Review And Innovation

Dear Dov Henis,

Thank you for your input. Please be aware that a significant part of
the process to Enhance Peer Review is "Continuous Review of Peer
Review." We will keep your comments under consideration.

The Enhancing Peer Review Team
http://enhancing-peer-review.nih.gov
"...fund the best science, by the best scientists, with the least amount
of administrative burden."

C. From earlier postings of mine:

"Peer Review" is, factually, a tool of a "Subversive Activities Control Board", a tool of the Science Establishment.

The most revolting corrupt aspect of peer review in science is its exploitation by the Science Establishment to tightly clamp its political and financial omni-everything power, rule, control and censorship, including stifling of any shred of scientific innovation not originated or not publicized via The Establishment's network.

The corruption is not inherent in the tool, but in the nature of the Science Establishment and in the characteristics of its obsequious functionaries.

"Implications Of Science And Technology Evolution"
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1&p=419

The AAAS and its affiliates and equivalent organizations, i.e. all the Science Establishment Guilds, loudly and pseudoscientifically promote and "profoundly respect" the "spiritual religious domain" as a real domain, a domain separate from the real science domain. They do this both because, unbelievably, they actually believe it and as a politically powerful tool in promoting towards themselves public esteem-acceptance and state-public financial support.

The peer review process is a tool of the Establishment. As long as the Science Establishment Guilds are what they now are and as long as they enjoy the public and state esteem they now have, and as long as Science and Technologhy are not seperated from each other conceptually and administratively but considered and handled as one faculty, the corruption of science cannot and will not be overcome. These 21st century technology culture aspects have been well inscribed and entrenched by Science's Big Brothers in the minds and conceptions of the public.

D. The lesson of the wikipedia-encyclopedia's "public-sourcing" product,

and of additional currently on-line "outside-Establishment-sourcing" science publishing start-ups is discouraging. IMO the GPeerReview is destined to end up similarly, i.e. as a cheaper, more available, second-hand product proudly claimed to be produced with the Establishment's rules-regulations-considerations even if "made in China" for faster and cheaper delivery and for more wide-spread availability.

Thus science publishing delivery will become faster and cheaper but the products will be made and cleared with today's combination of writing rules-regulations and peer-review ecclestiasticism that have been so deeply inscribed in the flock of the 21st century Science Establishment Church.

Dov Henis

(A DH Comment From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

A Mumbo Jumbo Gallop Poll
re Darwin's 200 finds just 39% of Americans 'believe' in evolution

http://firstread.msnbc.msn.com/archive/2009/02/12/1791814.aspx

The language and terms of this Gallup poll is a glaring example of...meaningles mumbo-jumbo...

A proper poll would present a brief scientific definition-description of Life's Evolution, summarized in numbered sentences or paras, and solicit YES-NO- ACCEPT of each of them.

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Life's Manifest
http://www.the-scientist.com/community/posts/list/112.page#578

Science, AAAS, Sacred Nature, Virtual Reality
Survival Requires Sacramentalism, Not Rationalism
Pseudoprofound Gibberish

A. Biologist discusses sacred nature of sustainability
http://www.eurekalert.org/pub_releases/2009-02/wuis-bds021109.php

B. From my earlier postings:

- It's The AAAS That Promotes Religion In Science And In Law
The AAAS and its affiliates and equivalent organizations, i.e. all the Science Establishment Guilds, loudly and pseudoscientifically promote and "profoundly respect" the "spiritual religious domain" as A REAL domain, a domain separate from the REAL, science, domain. They do this both because, unbelievably, they actually believe it and as a politically powerful tool in promoting their power and state-public support.

- On Science and Religion
"Evolutionary Biology Of Culture And Religion"
http://www.the-scientist.com/community/posts/list/20/122.page#492

Religion is a human virtual reality artifact, experienced only through sensory stimuli. Preoccupation with religious matters within a scientific frameworks contributes to corrosion and corruption of science and scientism by manifesting or implying acceptance of virtual reality as reality.
Everything is discussable scientifically. No limit. Including virtual matters and affairs. But for a scientific discussion the framework must be clearly defined. The totality of subjects that come under the classification "virtual" are not an exception. You can include in the discussion Pavlov and the modes and manners of exploiting virtuality in any area and towards any end.

- Why Pavlov smiled in 2008

Pavlov demonstrated effecting placebo phenomena in multicelled organisms by manipulation of their drives-reactions. Now placebo and imagination phenomena are demonstrated also in life's base organisms, in the genes and genomes of multicelled organisms, in our primal first stratum and 2nd stratum base organisms. A very good reason to smile.

Now an interesting chain is exposed to our view, the Genes-Virtual Reality Chain, a most intriguing Cultural Evolution Chain extending from the Genesis of genes to nowadays organisms' cultures, throughout life, which is a virtual reality existence, the cultures are evolving by virtual reality phenomena, exploitations and manipulations.

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Life's Manifest
http://www.the-scientist.com/community/posts/list/112.page#578

More Corruption Of Science By AAAS
Via "New Masters of Science"

I. AAAS: The New Masters of Science
http://www.sciencenews.org/view/generic/id/40906/title/AAAS_The_New_Masters_of_Science_
A new master's degree program is emerging that is creating "a new type of scientist" and a new professional class.

II. From "Societal Implications Of Science And Technology Evolution"
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1&p=419
Science And Technology Evolution Since The 1920s, And Its Societal-Social Implications

I posit that the nature of the evolution of science and technology since the 1920s has been the most significant molding factor of the present characteristics of our society, and that it is vitally important for charting the future course of our society to learn and understand this evolution.

A. Science and technology are clearly and distinctly two separate faculties, separate branches of learning and teaching. Yet since the 1920s the titles of these different faculties appear inseperably jointly everywhere.

B. Why is it that since the 1920s technology has been evolving dynamically whereas basic, non-applied, science has been progressing - in my opinion - at ever decreasing rate?

C. And what have been and what are the societal-social implications of the format of this evolution and of the present state of science and technology?

D. Definitions of terms for the subject of this thread:

- Science: state of knowledge attained by systematized thinking, studies and/or tests through established scientific methods.

- Technology: capability of and manner of practical application of knowledge.

III. It appears that the mundane term "technician of science" is a threat to the AAAS

Looks like the AAAS resorts to a virual-reality public-relations manipulation, to "Masters of Science" in lieu of the obviously factual plain and simple "technician of science", in order to allay apprehension that "technician of science" might have deleterious effects on its size and esteem and public impact...

Hypocrisy, hypocrisy...

Dov Henis

(Comments From The 22nd Century)
http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q--?cq=1

Life's Manifest
http://www.the-scientist.com/community/posts/list/112.page#578