On The Life Sciences Scene

Obama-Collins-AAAS, A Spiritual Harmony Team
A Disturbing Exasperation-Boding Harmony

A. "Collins nominated to head NIH"
http://www.sciencenews.org/view/generic/id/45420/title/Collins_nominated_to_head_NIH
The chemist — turned physician, turned geneticist — has a spiritual side as well.

B. "Prsdnt Obama Should Consider An Overdue Introspection"
http://www.the-scientist.com/community/posts/list/160/122.page#2388

C. For the attention of the Spiritual Harmony Team
"On the origin of origins" and on rationality
http://www.the-scientist.com/community/posts/list/160/122.page#2753

Dov Henis
(Comments From The 22nd Century)

Again And Again: It's Culture That Drives Evolution
Not Occasional Genetic Accidents

Re "Spontaneous speciation?"
http://www.the-scientist.com/blog/display/55825/

Again and again:

A. Earth's primal organisms, Genes, and their take-offs, all Earth organisms, are temporary energy packages. The more of them there are the more enhanced is the biosphere, Earth's life, Earth's storage of temporarily constrained energy. This Is Nature's Drive And Purpose Of Life. This Is The Origin, The Drive, The Archetype, Of Selected Modes Of Survival.

B. From http://www.physorg.com/news151319378.html
I have been presenting evidence for years that adaptation, i.e. culture, is the driver of evolution of all life including human and, yes, of all other, inanimate materials, and that genetic evolution is generally biased, not random.

NO NO NO. The drive of evolution is NOT RANDOM change followed by survival selection. It is biased, as explained in my "Updated Life's Manifest" and elaborated in my posts about the nature and role of culture in evolution. In evolution of ALL materials, including life.

C. From http://www.the-scientist.com/community/posts/list/160/122.page#2753
"Origin Of Origins"
Earth Life is but one specimen of myriad of materials being formed and attempting to survive for temporarily constraining energy. This is the essence of the ongoing Big Bang.

Dov Henis
(Comments From The 22nd Century)
Updated Life's Manifest May 2009
http://www.physforum.com/index.php?showtopic=14988&st=480&#entry412704
http://www.the-scientist.com/community/posts/list/140/122.page#2321

On The Origin And Tasks Of Brain Cells
"what all these new cells are good for"

A. From "Newborn brain cells"
http://www.eurekalert.org/pub_releases/2009-07/si-nbc070609.php

"big leap forward in understanding what all these newborn neurons might actually do. Their study, published in the July 10, 2009, issue of the journal Science, illustrates how these young cells improve our ability to navigate our environment. We believe that new brain cells help us to distinguish between memories that are closely related in space,"

"question is no longer whether neurogenesis exists but rather what all these new cells are actually good for"

B. From "Life And Darwinism, Tomorrow's Comprehension"
http://www.the-scientist.com/community/posts/list/112.page

From my postings way back in 2005, which cites genetic evidence/demonstration of the workings of human cultural evolution:

- From Science, 2 Sept 2005: "Page's team compared human and chimp Ys to see whether either lineage has lost functional genes since they split.

The researchers found that the chimp had indeed suffered the slings and arrows of evolutionary fortune. Of the 16 functional genes in this part of the human Y, chimps had lost the function of five due to mutations. In contrast, humans had all 11 functional genes also seen on the chimp Y. "The human Y chromosome hasn't lost a gene in 6 million years," says Page. "It seems like the demise of the hypothesis of the demise of the Y," says geneticist Andrew Clark of Cornell University in Ithaca, New York.

Chimp's genome has been continuing survival by physiologically adapting to changing environments.

- But look at this: From Science, Vol 309, 16 Sept 2005, Evolving Sequence and Expression:"An analysis of the evolution of both gene sequences and expression patterns in humans and chimpanzees...shows that...surprisingly, genes expressed in the brain have changed more on the human lineage than on the chimpanzee lineage, not only in terms of gene expression but also in terms of amino acid sequences".

Surprisingly...???

Human's genome continued survival mainly by modifying-controling its environment.

C. From "More On The Lifehood Of Genes"
http://www.the-scientist.com/community/posts/list/160/122.page

"Genes to Genomes to Monocellular Organisms to Multicellular Organisms"
http://www.articlesbase.com/science-articles/life-is-simpler-than-they-tell-us-817144.html

Now we can appreciate the fractal nature of life's evolution. It is ever-continuous ever-enhanced ever-complexed cooperation. Now we can understand why, and grosso modo how, the organs and processes and signals found in multicelled organisms have their historical origins in the life-cultures of monocells communities. And this includes modifying shape of monocells community in response to changed circumstances, functions of serotonin and melatonin and, yes, the evolution of neural cells and the neural systems with their intricate outer-membrane shapes and functions and their high energy consumption requirements.

And this includes also production of fresh genostem cells in monocells communities, in response to arising community needs. And this includes also a variety of means and mechanisms within cells community involved from sensing a need of fresh genostemcells through producing them and directing them to target locations where they are needed and committing them to the specific tasks in response to the new need.

D. Life is REALY simpler than they tell us in endless variations in AcademEnglish...

Dov Henis
(Comments From The 22nd Century)
Updated Life's Manifest May 2009
http://www.physforum.com/index.php?showtopic=14988&st=480&#entry412704
http://www.the-scientist.com/community/posts/list/140/122.page#2321

Of Flowers And Humans
Of Myopia In Evolution
entirely new explanation?

A. Darwin’s Mystery Of Appearance Of Flowering Plants Explained
http://www.sciencedaily.com/releases/2009/07/090713211621.htm

The researchers have consequently provided an entirely new explanation for what Charles Darwin considered to be one of the greatest mysteries with which he was confronted...

B. From "Life And Darwinism, Tomorrow's Comprehension"
http://www.the-scientist.com/community/posts/list/112.page

On The Origin And Tasks Of Brain Cells, "what all these new cells are good for"
http://www.the-scientist.com/community/posts/list/180/122.page#2822

Surprisingly...??? Human's genome continued survival mainly by modifying-controling its environment.

And AAAGAIN: For Nature genes are genes are genes. None are more or less important than the others. Genes and their take-offs, all Earth organisms, are temporary energy packages and the more of them there are the more enhanced is the biosphere, Earth's life, Earth's temporary storage of constrained energy. This is the origin, the archetype, of selected modes of survival.

C. Life is REALY simpler than they tell us in endless variations in AcademEnglish...

Dov Henis
(Comments From The 22nd Century)
Updated Life's Manifest May 2009
http://www.physforum.com/index.php?showtopic=14988&st=480&#entry412704
http://www.the-scientist.com/community/posts/list/140/122.page#2321

Rash Human Y Demising?
On The Male Sex Chromosome

A. On Human male sex chromosome, aaagain?

From "Male Sex Chromosome Losing Genes By Rapid Evolution, Study Reveals"
http://www.sciencedaily.com/releases/2009/07/090716201127.htm

"...we also know that most of the genes were not important for survival because they were lost, which led to the very different numbers of genes we observe between the once-identical X and Y. Although there is evidence that the Y chromosome is still degrading, some of the surviving genes on the Y chromosome may be essential, which can be inferred because these genes have been maintained for so long."

"...found evidence that some others are on track to disappear, as well."

B. From "Spontaneous speciation?"
http://www.the-scientist.com/blog/display/55825/

And from "On The Origin And Tasks Of Brain Cells"
http://www.the-scientist.com/community/posts/list/180/122.page#2822

And from "Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee"

http://www.nature.com/nature/journal/v437/n7055/full/nature04101.html

Chimp's genome has been continuing survival by physiologically adapting to changing environments, whereas Human's genome continued survival mainly by modifying-controling its environment.

C. AcademEnglish verbiage should be at least scientifically careful

The rate of "losing genes" by an organism is not a constant value of a natural law. It is induced and set mostly by the rate and nature of the change of culture of the organism, which is induced, in turn , by various circumstential factors...

IMO we can feel assured that the human Y is not on an accelerating course to oblivion...

Dov Henis
(Comments from 22nd century)

More On Web-Only Science Literature

A. Antiscientism Evangelism

During the last half of its 160 years long history the AAAS, the organization and Science-Establishment-Guild-TradeUnion of our "scientists" (whatever "scientists" means), has been The Antiscientism Evangelist on Earth.

It has been promoting ITS Science as The True Science, as a "universal religion" alongside and in addition to all "other spiritual" personal religions.

The AAAS explicitly considers that thus having two religions is in accordance with one of the definitions of "rationalism", i.e.: "reliance on reason as the basis for establishment of religious truth" ( whatever "religious truth" was when this definition was drawn up prior to comprehending that religion is a virtual reality affair), rationalism being most synonymous with science...

But by adopting THIS meaning of rationalism AAAS obviously and harshly disregards other definitions of rationalim:

- "a theory that reason is in itself a source of knowledge superior to and independent of sense perceptions"

- "a view that reason and experience rather than the nonrational are the fundamental criteria in assessing and solution of problems"

B. From "Science Web Posting vs TradeUnion Publishing"
http://www.the-scientist.com/community/posts/list/160/122.page#2717

And from "What to do about Iran"
http://www.the-scientist.com/community/posts/list/526.page#2613

What is the foundation-implications of the pretensions of self-designated "scientists" to special relevance-standing on ANY issue? Is it the (AAAS) Science TradeUnion membership that blows up the pretentious ego? Or is it their imbued alter-religious sense?

C. Is 21st century SCIENCE prepared and capable to update-reform its charter and image,

its organizational and its essential nature, to graduate into the 21st century and to adopt also scientific web-only literature?

Wondering,

Dov Henis
(Comments From The 22nd Century)
Origin Of Origins
http://www.the-scientist.com/community/posts/list/160/122.page#2753

Old Genes Can Learn New Tricks
Psalms 115,5-6

A. "Dogs, maybe not, but old genes can learn new tricks"
http://www.physorg.com/news161280793.html

B. "They have eyes, but they can not see, They have ears, but they cannot hear"
(Psalms 115,5-6)

Exasperating. "Scientists" keep ruminating again and again stale verbiage about genes with determination not to see that genes are organisms.

C. About time for life sciences to assimilate, to internalize, the lifehood of genes,

starting with search-surfing "on the lifehood of genes" or "on the pavlovian behaviour of genes".

Suggesting,

Dov Henis
(Comments From The 22nd Century)
Origin Of Origins
http://www.the-scientist.com/community/posts/list/160/122.page#2753

Of Human Conceitedness And Scientific Staleness

A. Pearls from "Common fish species has 'human' ability to learn"
http://www.physorg.com/news164423377.html

- "The findings show that big brains, like those in humans, are not necessarily needed as a pre-requisite for cumulative culture."

- "The researchers say the findings contribute to the understanding of brain evolution and the types of brain required for certain cognitive functions, both in humans and animals."

- "But our results suggest brain size isn't everything when it comes to the capacity for social learning."

- "These fish are obviously not at all closely related to humans, yet they have this human ability to only copy when the pay off is better than their own. You might expect this ability in animals who are closely related to humans. In the case of the nine-spined stickleback, they have most likely adapted to their local ecology."

B. About time for life sciences to assimilate, to internalize, that it is culture that drives genetics, NOT genetics that drives culture,

starting with search-surfing "Dov Henis : It is culture that drives genetics, not genetics that drives culture"

Suggesting,

Dov Henis
(Comments From The 22nd Century)
http://profiles.yahoo.com/blog/2SF3CJJM5OU6T27OC4MFQSDYEU
Origin Of Origins
http://www.the-scientist.com/community/posts/list/160/122.page#2753

Is Endless Gibberish Enlarging Scientists' Brain ?
On Theme And Variations

A. From "Competition may be reason for bigger brain"
http://www.physorg.com/news164901829.html

- "The team found that social competition is the major cause of increased cranial capacity."

- "Our research tells us that competition, whether healthy or not, sets the stage for brain evolution."

B. About time for life sciences to assimilate, to internalize, the theme of brain evolution and its variations

"On The Origin And Tasks Of Brain Cells"
http://www.the-scientist.com/community/posts/list/180/122.page#2822

About time for life sciences to assimilate, to internalize, that it is culture that drives genetics, and that genes-genomes survive mainly by evolving their culture of manipulating-modifying-controling their environment.

"Scientists" might start further evolving their thinking by starting with search-surfing "Dov Henis : It is culture that drives genetics, not genetics that drives culture".

Suggesting,

Dov Henis
(Comments From The 22nd Century)
http://profiles.yahoo.com/blog/2SF3CJJM5OU6T27OC4MFQSDYEU
Origin Of Origins
http://www.the-scientist.com/community/posts/list/160/122.page#2753

Scientists Keep Chasing Their Selfmade Gibbering Tail

A. "Dark Matter May be Easier to Detect than Previously Thought"
http://www.physorg.com/news169121408.html

And

"Dark Energy From the Ground Up: Make Way for BigBOSS"
http://www.physorg.com/news168858441.html

B. On The "Origin Of Origins"
http://www.the-scientist.com/community/posts/list/160/122.page#2753

http://www.physforum.com/index.php?showtopic=14988&st=525&#entry420991

Enough Is Enough!

Beyond Einstein-Hubble And Beyond Darwin

Dark Matter-Energy And Higgs Particle?

Energy-Mass Superposition
The Fractal Oneness Of The Universe
All Earth Life Creates and Maintains Genes

Dov Henis
(Comments from 22nd century)
http://profiles.yahoo.com/blog/2SF3CJJM5OU6T27OC4MFQSDYEU

Human Virtual Reality And Impatience For Science

A. All of lifes, including human life, is a virtrual reality affair

The environment and setting of life are real, sensed and assessed by biological mechanisms and processes, that yield virtual conceptions, which lead to and trigger real reactions and consequences, reality.

However, the existential conceptions of humans differ from those of other Earth organisms both in the characteristics of the parameters of reality and in the extent and characteristics of the virtuality parameters. In humans the existential virtual parameters are far more extensive and of far more real life, reality, consequences than in other Earth organisms.

B. Humans' extensive existential virtual reality and impatience for science are distinctive of the very early age of its present existential culture

All life forms are Pavlovian, since the organisms genes-genomes are pavlovian. Pavlovian organisms can and do learn. The distinction of the present state of the young human culture is that a good number of humans are also Pavlovs, capable of conceiving reality closely and of leading and inducing adoption of ever more realistic culture by many other humans.

However, the majority of humanity is still bound by virtual conceptions. Historical phenotypical human virtual conceptions still dominate almost all aspects of life of all human individuals and groups, including those of most "scientists".

It takes a determined effort to overcome the natural reluctance to extract oneself from the personal and social secure old Pavlovian routine, to exercise an individual critical assessment of established virtual concepts and to accordingly modify attitudes and actions.

IMO this is the root of impatience with science by both the general public and most scientists, who are bound by virtual concepts acquired-adopted in the course of their education and of their professional surroundings.

It would take a lengthy patient steadfast effort to indoctrinate ever more humans to adopt ever more scientifically rational life culture.

Suggetsing,

Dov Henis
(Comments from 22nd century)
On The Origin Of Origins
http://www.the-scientist.com/community/posts/list/160/122.page#2753
http://www.physforum.com/index.php?showtopic=14988&st=525&#entry420991

The 21st Century Dark-Realm Rush By Science
is a shuddering shameful futile waste

The 21st century Dark-Realm Rush of science in search of Dark Energy-Matter is a shuddering and shameful waste of menpower and of many other resources on a commonsensical futile chase of a grand 100 year old virtual hallucination.

Again and again : dark energy-matter scientists keep chasing their selfmade gibbering tail.

And again and again : On The Origin Of Origins
http://www.the-scientist.com/community/posts/list/160/122.page#2753

http://www.physforum.com/index.php?showtopic=14988&st=525&#entry420991

Enough is enough!

Exercise critical thinking beyond Einstein-Hubble and beyond Darwin.

Dark Matter-Energy And Higgs Particle ???

Ponder energy-mass superposition and the Fractal Oneness of the universe.

Ponder the implication of the commonsensical universe scheme on the origin and nature of life.

Suggesting,

Dov Henis
(Comments from 22nd century)
http://profiles.yahoo.com/blog/2SF3CJJM5OU6T27OC4MFQSDYEU

The Basic Implications Of E=Total[m(1 + D)]
a recapitulation

A. Its essential statement

"Extrapolation of the expansion of the universe backwards in time to the early hot dense "Big Bang" phase, using general relativity, yields an infinite density and temperature at a finite time in the past. At age 10^-35 seconds the Universe begins with a cataclysm that generates space and time, as well as all the matter and energy the Universe will ever hold."

E = Energy content of the universe
m = mass content of the universe
D = distance, Total = in all spatial directions, from the point of Big-Bang, of singularity's energy-mass superposition

At D=0, E was = m and both E and m were, together, all the energy and matter the Universe will ever hold. Since the onset of the cataclysm, E remains constant and m diminishes as D increases.
The increase of D is the initial inflation, followed by the ongoing expansion, of what became the galactic clusters.

At 10^-35 seconds, D was already a fraction of a second above zero. This is when gravity starts. This is what started gravity. At this instance starts the energetic space texture, starts the straining of the space texture, and starts the space-texture-memory, gravity, that most probably will eventually overcome expansion and initiate re-impansion back to singularity.

B. Some of its further essential implications beyond Einstein-Hubble and re classical-quantum physics

And again and again : "On The Origin Of Origins"
http://www.the-scientist.com/community/posts/list/160/122.page#2753

1. It promotes commonsensical scientific critical thinking beyond Einstein-Hubble.

The universe is the archetype of quantum within classical physics, which is the fractal oneness of the universe.

Astronomically there are two physics. A classical Newtonian physics behaviour of and between galactic clusters, and a quantum physics behaviour WITHIN the galactic clusters.

The onset of big-bang's inflation, the cataclysmic resolution of the Original Superposition, started gravity, with formation - BY DISPERSION - of galactic clusters that behave as classical Newtonian bodies and continuously reconvert their original pre-inflation masses back to energy, thus fueling the galactic clusters expansion, and with endless quantum-within-classical intertwined evolutions WITHIN the clusters in attempt to delay-resist this reconversion.

2. There is no call, no need, for any dark energy. The energy of the universe is conserved. The mass of the universe is conserved in the form of energy, the energy fueling the clusters expansion. At the next universal singularity, at the next D = 0, there will again be E = m for a small fraction of a second...just wait and see...

Following Newton (1) gravity is decreased when mass is decreased and (2) acceleration of a body is given by dividing the force acting upon it by its mass. By plain common sense the combination of those two 'laws' may explain the accelerating cosmic expansion of galaxy clusters and the laws that drive it, based on the E/ m/ D relationship suggested above.

3. There is no call, no need, for a Higgs Particle.

The resolution of energy-mass superposition is reverted when D = 0. Shockingly sad, but must be soberingly faced rationally.

C. Its implications re the origin and nature of life beyond Darwin, re selection for survival

For Nature, Earth's biosphere is one of the many ways of temporarily constraining an amount of energy within a galaxy within a galactic cluster, for thus avoiding, as long as possible, spending this particularly constrained amount as part of the fuel that maintains the clusters expansion.

Genes are THE Earth's organisms and ALL other organisms are their temporary take-offs.

For Nature genes are genes are genes. None are more or less important than the others. Genes and their take-offs, all Earth organisms, are temporary energy packages and the more of them there are the more enhanced is the biosphere, Earth's life, Earth's temporary storage of constrained energy. This is the origin, the archetype, of selected modes of survival.

The early genes came into being by solar energy and lived a very long period solely on direct solar energy. Metabolic energy, the indirect exploitation of solar energy, evolved at a much later phase in the evolution of Earth's biosphere.

Dov Henis
(Comments from 22nd century)

New Insights Into Life Evolution???
New indeed...

A. New Insights Into Life Evolution?

(1) "Major insights into evolution of life reported"
http://www.physorg.com/news169907476.html

(2) "Researchers identify 2 key pathways in adaptive response"
http://www.physorg.com/news170136477.html

B. And some old insights into life evolution

(1) "The Basic Implications Of E=Total[m(1 + D)] "
http://www.the-scientist.com/community/posts/list/180/122.page#3108
a recapitulation

(2) "Updated Life's Manifest May 2009"
http://www.the-scientist.com/community/posts/list/140/122.page#2321
Recapitulation of some earlier notes on the
Scientific Comprehension Of The Origin, Drive, Nature And Purpose Of Life

(3) "More on the lifehood of genes that makes each and all organisms alive"
http://www.the-scientist.com/community/posts/list/160/122.page
Genostemness Induction

Dov Henis
(Comments From The 22nd Century)
EVOLUTION Beyond Darwin 200
http://www.the-scientist.com/community/posts/list/100/122.page#1407

Proteins Not Early Life's Building Blocks

A. "Comet dust harbors life's building blocks"
http://www.sciencenews.org/view/generic/id/46570/title/Comet_dust_harbors_lifes_building_blocks
Samples collected from a comet’s halo suggest comets could have carried amino acids - building block of proteins - to the early Earth...

B. Proteins not early life's building blocks

Proteins have nothing to do with the initiation and evolution of early Earth's life, the biosphere. RNA's, followed with DNA's, were "life's building blocks", the constituents of the early independent genes, Earth's primal organisms.

Earliest and present primary Earth life are, obviously and commonsensibly, and therefore scientifically, genes. Plain and simple. All other organisms, regardless of complexity, are take-offs of genes. Early life was formed and maintained with DIRECT sunlight. Hence ubiquitous life sleep. Biometabolism, dependence of life on INDIRECT sunlight energy, was a very late phase of Earth's life evolution.

See "Updated Life's Manifest May 2009"
http://www.the-scientist.com/community/posts/list/140/122.page#2321

Dov Henis
(Comments From The 22nd Century)

(Old posting, slightly modified)

Teleology Is Universal
And Explains Life's Amino Acids Chirality

A. Amino Acids Chirality In Life
http://scienceandreason.blogspot.com/2009/04/amino-acid-chirality.html

B. Again, the probable reason for life's amino acids chirality:

Darwinian evolution started at life's day one, with the genesis of Earth's primal organisms, the replicating oligomers, the pre-archaea genes. It started under yet-unknown energetic conditions, by a serendipitous occurrence, most probably with oligomeric RNA conformations, in sunlight-bathed soup containing all their essential molecular progenitors. These conformations happened to maintain a balance of energy in the direction of their polymerization to lengths precipitated out of their soup as determined by the nature and conditions of the soup.

The sugars and their appended nucleotide bases, that together with the phosphates are the structural components of genes, of life's primal organisms, are chiral. There probably is an energetic advantage in homochirality and chiral homogeneity for the self-replication of these biopolymers.

This serendipitous occurrence set up a matrix-field of energy with a potential extended between its source, on-Earth incoming energy, and the precipitating organisms, the genes. This was the genesis of the ongoing formation and maintenance of Earth's biosphere.

And since the biosphere had thus started it could only evolve in the directions of more favorable energy balances-packages and towards stabler energy-packages conformations, in the direction of survival. Earth's biosphere embarked on the course of its evolution.

C. Some definitions, with "end" replacing dictionary's 'cause' or 'design' or 'purpose'

- tele-, telos end

- teleology = a doctrine explaining phenomena by final end; the fact or character attributed to nature or natural processes of being directed toward a specific end; the referral to the end of universe as an explanation of natural phenomena.

teleonomy = the quality of survival of structure or function in living organisms due to evolutionary adaptation.

D. Teleology exist in all nature's systems, both living and nonliving. It is universal.

The universe, with all its sub-systems, including life, is a continuously evolving fractal system, with energy as the base element of everything. Cosmic evolution is evolution of energy. At the beginning of the present cosmic cycle was the energy singularity. At its end there will be a small amount of mass and an infinite dispersion of the beginning energy. In-between, the universe undergoes continuous evolution, consisting of myriad energy-to-energy and energy-to-mass-to-energy transformations.

Evolution ensues from and consists of systems modifications, "mutations", inherently ever more of them as more new options arise for the systems, be they non-living or living.

Life systems, like other mass systems, are temporary packages of constrained energy. On Earth they are components of the grand, temporarily constrained, biosphere energy store. Their temporary survival 'end' is to enhence and maintain their bio matrix, the biosphere.

Modifications of genomes functional capabilities, of genes expressions, can be explained by the feedbacks they receive from their (3rd stratum) cellular organisms, feedbacks from their culture-life-experiences. The route-modification selection of a replicating gene, when it is at its alternative-splicing-steps junctions, is biased by the feedback received by the genome. THIS IS HOW LIFE EVOLUTION COMES ABOUT.

For non-life systems there is no mediating culture. The interaction between environments and systems are direct, in the direction towards the 'end' of the present phase of the universe.

Suggesting,

Dov Henis
(Comments From The 22nd Century)
Updated Life's Manifest May 2009
http://www.physforum.com/index.php?showtopic=14988&st=480&#entry412704
http://www.the-scientist.com/community/posts/list/140/122.page#2321

On Natural Laws
My Comprehension

A natural law = A theory that has been observed to occur many times and found to always re-occur.

Laws of nature, like grammer of language, have no self-existence. They are not Directives. They are a summary of observed practices, of observed occurrences. All natural laws are observed occurrences of evolutions in the universe.

Dov Henis
(Comments From The 22nd Century)
Updated Life's Manifest May 2009
http://www.physforum.com/index.php?showtopic=14988&st=480&#entry412704
http://www.the-scientist.com/community/posts/list/140/122.page#2321
EVOLUTION Beyond Darwin 200
http://www.the-scientist.com/community/posts/list/100/122.page#1407

Mutants With An Ironic Twist

Life Scientists Are All Myopic,
They Think We Are All Mutants...

A. From "We are all mutants"
http://www.eurekalert.org/pub_releases/2009-08/wtsi-waa082509.php

- "Understanding mutation rates is key to many aspects of human evolution and medical research: mutation is the ultimate source of all our genetic variation and provides a molecular clock for measuring evolutionary timescales. Mutations can also lead directly to diseases like cancer. With better measurements of mutation rates, we could improve the calibration of the evolutionary clock, or test ways to reduce mutations, for example."

- "To establish the rate of mutation, the team examined an area of the Y chromosome. The Y chromosome is unique in that, apart from rare mutations, it is passed unchanged from father to son; so mutations accumulate slowly over the generations."

B. Genetic accidental "mutations" are minor contributors to genetic evolution

See "Evolution, Genetics And Culture"
http://www.the-scientist.com/community/posts/list/160/122.page#2485

Adaptation is culture. And culture is the driver of Universal Evolution, of all evolutions.
See "Rethink Unified Field Theory And Evolution"
http://www.the-scientist.com/community/posts/list/60/122.page#982

and see "Spontaneous Speciation?"
http://www.physorg.com/news151319378.html

C. An ironic twist...

Searching for genetic change rate in the human Y chromosome is searching at night for a lost coin under the street light only.

See "Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee"
http://www.the-scientist.com/community/posts/list/180/122.page#2887

And see especially "On The Origin And Tasks Of Brain Cells"
http://www.the-scientist.com/community/posts/list/180/122.page#2822

The human Y-linked genes are indeed conspicuously preserved. The irony is that this is part of THE proof that genetic changes are NOT brought about by "mutations", as it is culture that drives genetic changes!

Dov Henis
(Comments From The 22nd Century)

From Genes To Identity

A. "From Axons to Identity: Neurological Explorations of the Nature of the Self by Todd E. Feinberg"
http://www.sciencenews.org/view/generic/id/46762/title/From_Axons_to_Identity__Neurological_Explorations_of_the_Nature_of_the_Self_by_Todd_E._Feinberg

B. "Life Is Simpler Than They Tell Us" , a reposting:

Genes to Genomes to Monocellular to Multicellular Organisms;
Direct Sunlight to Metabolic Energy, Too;
Triptophan to Serotonin to Melatonin to Neural System.

A. Triptophan to Serotonin to Melatonin

Melatonin is a hormone secreted by the human pineal gland during night-time darkness. It is now marketed in the US as a nutritional supplement. The hormone is an indoleamine compound derived from the essential amino acid L-tryptophan, with serotonin as an intermediate precursor.

Tryptophan is one of eight essential amino acids, not produced by the body but coming from the diet. The additional fourteen amino acids are produced metabolically.

In the brain, tryptophan converts to serotonin, the neuro-transmitter. Tryptophan is the only source for serotonin in the brain. Insufficient L-tryptophan in the diet is a cause of many severe biological malfunctions.

Some serotonin is converted in the pineal gland to melatonin, the hormone involved in intercell processes during sleep time.

B. Sunlight to Metabolic Energy

Bio-clocks are products of the innate sun-dictated active-inactive pattern of genes and genomes, parents of Earth's life. During life genesis and its early evolution direct sunlight was the only source of their usable energy. This situation persistrd well into the evolution of the early monocellular organisms, and both genes and genomes display, therefore, innate "inactive-sleep" phenomena.

The incorporation of mitochondria with some cells innitiated the metabolic bio production of bio usable energy and furnished the evolving monocellular organisms with new, additional, flexibly available local energy. This development opened up a variety of courses of evolutions of cultures of monocells communities.

C. Individual Monocells to Cooperative Monocells-Communities

As individual independent genes aggregated to cooperative genes communes, genomes, so individual monocells aggregated cooperatively into monocellular communities.

From "Life Is A Cooperative Affair" (Sept 2005)

http://profiles.yahoo.com/blog/2SF3CJJM5OU6T27OC4MFQSDYEU?num=5&max=160&start=39

"Life has always been and still is a fractal affair, repetition of phenomena on ever more complex scale. It cannot be otherwise; it evolves. And surviving-proliferating life has always been a cooperative affair since cooperation is most successful for overall survival/proliferation."

Cooperation requires all sorts of interactions, including maintenance, protection and foraging for food-energy. Organisms' interactions are "cultures". Cultures require "cultural energy". Melatonin and some proteins are dark-and-light que signals evolved by the monocells communities for timing intercells processes when the intracells processes are at "sleep-inactive" state. Melatonin is a derivative of serotonin a derivative of triptophan, and proteins are genes' toolings, energy-dependent metabolism products.

D. Monocellular to Multicellular Organisms, Monocells Culture to Neural System

Now we can appreciate the fractal nature of life's evolution. It is ever-continuous ever-enhanced ever-complexed cooperation. Now we can understand why, and grosso modo how, all the organs and processes and signals found in multicelled organisms have their origins in the monocells communities. And this includes the functions of serotonin and melatonin and, yes, the evolution of neural cells and the neural systems with their intricate outer-membrane shapes and functionings and with their high energy consumption requirements.

Now, circa four billion years after initial genesis-evolution with direct sun's energy followed with evolution with also indirect, bio, sun's energy, some of Earth life, we humans, find ouselves short of energy and in need of exploiting again more, and more direcly, our sun's energy...

Dov Henis
(Comments From The 22nd Century)
Updated Life's Manifest May 2009
http://www.physforum.com/index.php?showtopic=14988&st=480&#entry412704
http://www.the-scientist.com/community/posts/list/140/122.page#2321
EVOLUTION Beyond Darwin 200
http://www.the-scientist.com/community/posts/list/100/122.page#1407

On The Antedeluvian Conceptions
On "the genetic book of instructions"

A. From "Domesticated silkworms’ secrets", posted by sciencenews.org

http://www.sciencenews.org/view/generic/id/46774/title/Domesticated_silkworms%E2%80%99_secrets

"After mapping the genetic book of instructions for wild and domesticated silkworms, scientists identify changes associated with the taming of these caterpillars."

B. Religious antedeluvian conceptions

It grates on the nerves and angers you.

Science, having been turned by the present science guild-tradeunion-establishment into a pseudoreligion and carrying on accordingly, also politically, adheres religiously to antedeluvian conceptions.

The genome is "the genetic book of instructions". Indeed.

The multigenes organism consisting of a cooperative commune of its member genes, the 2nd stratum organism, is a "genetic book of instructions"...

C. When will present "Science" cast off its religious tradeunion gibbering mantras?

Dov Henis
(Comments From The 22nd Century)
Updated Life's Manifest May 2009
http://www.physforum.com/index.php?showtopic=14988&st=480&#entry412704
http://www.the-scientist.com/community/posts/list/140/122.page#2321