Haematopoietic cell gene therapy with foamy viruses :The Scientist [26/7/2001]

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by Tudor Toma

RESEARCH ROUND-UP

Haematopoietic cell gene therapy with foamy viruses

A new vector system based on foamy viruses from the spumavirus family can be used for gene transfer into murine haematopoietic stem cells.

Email: Tudor Toma - ttoma@mail.dntis.ro
News from The Scientist 2001, 2(1):20010726-03

Published

26 July 2001

Transfer of therapeutic genes into haematopoietic stem cells can potentially cure blood disorders such as X-linked severe combined immunodeficiency. But human stem cells are relatively intractable to the available viral vectors. In August Blood, George Vassilopoulos and colleagues from University of Washington, Seattle, describe a new vector system based on foamy viruses from the spumavirus family that can be used for gene transfer into murine haematopoietic stem cells.

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