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Mast cell survival gene
Email: Tudor Toma - t.toma@ic.ac.uk News from The Scientist 2001, 2(1):20011213-02
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In an allergic reaction mast cells degranulate, but survive the process and can be reactivated to respond to a subsequent allergen challenge by mechanisms that remain unclear. In December Journal of Experimental Medicine, Zou Xiang and colleagues from Uppsala University, Sweden, show that the A1 gene is central to FcεRI-induced mast cell survival, while having no obvious role in mast cell development.
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