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Bop controls ventricle formation
Email: Tudor Toma - t.toma@ic.ac.uk News from The Scientist 2002, 3(1):20020408-03
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Defects in cardiomyocyte differentiation and cardiac morphogenesis cause heart malformations affecting almost one in every 100 children, but the mechanisms that regulate such events remain largely unknown. In April 1 online Nature Genetics, Paul Gottlieb and colleagues from University of Texas at Austin, US, show that Bop encodes a muscle-restricted protein that is essential for cardiac differentiation and morphogenesis (Nat Genet 2002, DOI: 10.1038/ng866).
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