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Building better gene vectors
News from The Scientist 2002, 3(1):20020918-02
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Gene therapy requires highly efficient recombinant adenoviral vectors that can induce lifelong therapeutic gene expression, but it has been unclear how such a vector can best be engineered. In September 16 Nature Biotechnology, Stephen Yant and colleagues at Stanford University School of Medicine, show that a gene-deleted adenovirus–transposon vector can stabilize transgene expression in vivo (Nature Biotechnology, DOI:10.1038/nbt738, September 16, 2002).
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