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Life span receptors
News from The Scientist 2002, 3(1):20021205-02 doi:10.1186/20021205-02
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The precise genes involved in the control of ageing have been unclear, but several studies from invertebrates studies suggest that some of these life span genes encode components of the insulin or insulin-like signaling pathways. In December 5 Nature, Martin Holzenberger and colleagues at the INSERM, France, show that IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice (Nature doi:10.1038/nature01298, December 5, 2002).
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