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Generating robustness
Email: Jonathan Weitzman - jonathanweitzman@hotmail.com News from The Scientist 2003, 4(1):20030102-02 doi:10.1186/20030102-02
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Gene knockouts often fail to reveal phenotypes, suggesting that biological systems are laden with compensation mechanisms, which might involve functional redundancy between duplicated genes or between alternative pathways and networks. In the January 2 Nature, Zhenglong Gu and colleagues describe a genome-wide evaluation of genetic robustness against null mutation (Nature, 421:63-66, January 2, 2003).
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