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Gene exchange in trypanosomes
Email: Richard Robinson - rrobinson@nasw.org News from The Scientist 2003, 4(1):20030227-03 doi:10.1186/20030227-03
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Trypanosoma cruzi — the causative agent of Chagas' disease — is a protozoan parasite that has life cycle stages in both mammalian and insect hosts. Different genetic forms of T. cruzi are known, but it has been thought that its propagation has been primarily clonal, without gene exchange between clones of different genotypes. In the February 27 Nature, Michael Miles and colleagues at the London School of Hygiene and Tropical Medicine, demonstrate that T. cruzi do exchange genes, and that the mechanisms of exchange are multiple and unusual (Nature, 421:936-939, February 27, 2003).
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