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Aging mitochondria favor diabetes
Email: Tudor P Toma - t.toma@imperial.ac.uk News from The Scientist 2003, 4(1):20030516-05
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Type 2 diabetes mellitus is a chronic metabolic disorder associated with insulin resistance and is common in those over the age of 60, but the mechanisms that cause insulin resistance later in life have been unclear. In the May 16 Science, Kitt Falk Petersen and colleagues at Yale University School of Medicine show that an age-associated decline in mitochondrial function contributes to insulin resistance in the elderly (Science, 300:1140-1142, May 16, 2003).
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