Advertisement
Survey Series
Institutions
For Advertisers
|
|
||||
|
Faulty adaptor linked to leukemia
Email: Tudor P Toma - t.toma@imperial.ac.uk News from The Scientist 2003, 4(1):20030522-01
|
||||
|
|
||||
|
Acute lymphoblastic leukemia (ALL) is the commonest form of childhood cancer and results from clonal proliferation of transformed hemopoietic cells, caused by genetic alterations. Most cases arise from B-cell clones arrested at the pre–B-cell stage of differentiation, but the molecular events involved have been unclear. In the May 22 Nature, Hassan Jumaa and colleagues at the University of Freiburg show that the somatic loss of the adaptor protein SLP-65 is one of the primary causes of childhood pre-B ALL (Nature, 423:452-456, May 22, 2003).
|
|
|||||||||
|
|||||||||
|
