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How to build an artery
Email: Joe Bateman - Joseph.bateman@cancer.org.uk News from The Scientist 2003, 4(1):20030604-01
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During development, the mammalian circulatory system is fixed in place before blood-flow commences. Different sets of genes control artery and vein formation, long before the vessels can be distinguished on the basis of direction of blood flow. This understanding has been mainly due to the discovery that vascular endothelial growth factor (Vegf) is necessary for arterial development.
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