NOD1 ligand confirmed :The Scientist [9/6/2003]

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by Tudor P Toma

RESEARCH ROUND-UP

NOD1 ligand confirmed

Email: Tudor P Toma - t.toma@imperial.ac.uk
News from The Scientist 2003, 4(1):20030609-01

Recent evidence suggests that the nucleotide-binding oligomerization domain protein 1 (NOD1) has an important role in bacterial recognition and may function as a specific host pattern recognition receptor (PRR) in intracellular compartments. In the June 8 advanced online publication of Nature Immunology, Mathias Chamaillard and colleagues at the University of Michigan Medical School, confirm NOD1 as essential in host recognition of bacterial peptidoglycan containing diaminopimelic acid (Nature Immunology, DOI:10.1038/ni945, June 8, 2003).


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