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Bladder biofilms
Email: Tudor Toma - t.toma@imperial.ac.uk News from The Scientist 2003, 4(1):20030704-03
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Strains of uropathogenic Escherichia coli (UPEC) cause the majority of all urinary tract infections. Host defense mechanisms and antibiotic treatments kill most of the bacteria, but some can remain within the bladder tissue. However, the mechanisms involved in bacterial persistence within the urinary tract have been unclear. In the July 4 Science, Gregory G. Anderson and colleagues at the Washington University School of Medicine show that E. coli forms intracellular bacterial biofilm-like pods in bladders, favoring the recurrence of urinary tract infections (Science, 301:105-107, July 4, 2003).
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